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Anal squamos cell cancer

Estimated new cases and deaths from anal, anal canal, and anorectal cancer in the United States in [ 1 ]. The initial evaluation of a patient with anal cancer will include a careful clinical examination of the inguinal region and biopsy of any palpable lymph nodes. Anal cancer is usually curable. Overall, the risk of anal cancer is rising due to increased incidence of human papilloma virus HPV infection. Data suggest that certain sexual practices, such as receptive anal intercourse or a high lifetime number of sexual partners, portend an increased risk of anal cancer. These practices may have led to an increase in the number of individuals at risk of infection with HPV.
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What Is Anal Cancer?

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Anal Cancer - Symptoms, Diagnosis & Treatment | MD Anderson Cancer Center

Metrics details. The incidence of anal squamous cell carcinoma SCC has been steadily growing globally in the past decade. Clinical data on anal SCC from China are rare. We conducted this study to describe the clinical and epidemiological characteristics of anal SCC in China and explore prognostic factors of outcomes among patients with anal SCC. We audited demographic characteristics, relevant symptoms, risk factors, treatment modalities and outcomes for patients diagnosed with anal SCC at 11 medical institutions in China between January and July
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Anal Cancer Treatment (PDQ®)–Health Professional Version

The incidence of anal cancer has increased during the second half of the 20th century, with an incidence rate over 2. Its risk factors are human papillomavirus infection, a history of sexually transmitted diseases, a history of vulvar or cervical carcinoma, immunosuppression related to human immunodeficiency virus infection or after organ transplantation, haematological or immunological disorders, and smoking. The diagnosis requires clinical examination, palpation of the inguinal lymph nodes, high resolution anoscopy followed by fine-needle aspiration biopsy or core biopsy.
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Anal cancers are rare tumours; however, the incidence is increasing in both men and women. Changing trends in sexual behaviour, smoking, and infection with the human papillomavirus are thought to be responsible for the increase. The standard systemic treatment of metastatic disease remains cisplatin and 5-fluorouracil, and aside from several non-randomised small phase II trials there has been no real progress over the past two decades.
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